By Kyle J. Norton
Every day the scalp loses about 100 hairs and they will grow back in 5-6 weeks. However, in older men, hair loss was associated with the increase of levels of by-product prolactin of testosterone-induced the conversion of testosterone to gihydro-testosterones DHT, a leading cause in the promotion of hair growing back thinner or not grown back at all.
Conventionally, Minoxidil, a topical medicine approved by The U.S. Food and Drug Administration (FDA) was found to stop hairs from getting thinner and stimulate hair growth on the top of the scalp with a number of side effects.
Dr. Rossi A, the lead scientist at the University Sapienza of Rome in the evaluation of the effects of
oral Minoxidil wrote, ” Minoxidil is a potassium channel opener, causing hyperpolarization of cell membranes and it is also a vasodilator, it is speculated that, by widening blood vessels and opening potassium channels, it allows more oxygen, blood, and nutrients to the follicle”.
And, “The most common adverse reactions of the topical formulation are limited to irritant and allergic contact dermatitis on the scalp. There have been cases of allergic reactions to the nonactive ingredient propylene glycol, which is found in some topical solution especially if they are galenic”.
Therefore, if you are using the aforementioned product for the treatment of hair loss, please make sure you know all the side effects for preventive measure.
With an aim to find a potential ingredient for the treatment of hair loss, researchers evaluated the efficacy of 5% hexane extract of Curcuma aeruginosa (turmeric), a botanically derived inhibitor of 5α-reductase and 5% minoxidil in the treatment of androgenetic alopecia.
The study included 87 men with androgenetic alopecia (AGA) randomized to receive 5% Curcuma aeruginosa, 5% minoxidil, combination formulation (5% hexane extract of Curcuma aeruginosa + 5% minoxidil) or placebo, twice daily for 6 months.
In other words, treatment with 5% minoxidil and 5% C. aeruginosa extract shoed some degrees of hair regrowth without affecting hair shedding.
Based on the results, researchers wrote in the final report, “In men with hair loss in the vertex area of the scalp, the combination of 5% hexane extract of C. aeruginosa and 5% minoxidil slowed hair loss and increased hair growth”.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it’s news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada – Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Curcuma aeruginosa, a novel botanically derived 5α-reductase inhibitor in the treatment of male-pattern baldness: a multicenter, randomized, double-blind, placebo-controlled study by Pumthong G1, Asawanonda P, Varothai S, Jariyasethavong V, Triwongwaranat D, Suthipinittharm P, Ingkaninan K, Leelapornpisit P, Waranuch N. (PubMed)
(2) Germacrene Analogs are Anti-androgenic on Androgen-dependent Cells by Srivflai J, Khorana N, Waranuch N, Wisuitiprot W, Suphrom N, Suksamrarn A, Ingkaninan K. (PubMed)
(3) Minoxidil use in dermatology, side effects and recent patents by Rossi A1, Cantisani C, Melis L, Iorio A, Scali E, Calvieri S. (PubMed)