Healthy Food Onion Processes Anti Hypertensive Effects

By Kyle J. Norton

Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood. High blood pressure is a condition associated with abnormally high blood pressure in the arteries.

High blood pressure is also a condition of a cluster of metabolic syndrome involved in the risk of cardiovascular disease and diabetes.

If the blood pressure stays high over time, it not can damage the heart muscle but also the body in many ways.
According to the statistic from the CDC, 1 of 3 U.S. adults or about 75 million people is living with high blood pressure. Unfortunately, only about half (54%) of these people have their high blood pressure under control.
There is no single cause of high blood pressure, 
* Most unpreventable risk factors are family history, age, gender, ethnicity, and chronic kidney disease.
* Most preventable high blood pressure risk factors are physical inactivity, overweight or obese, unhealthy diet, smoking, and excessive alcohol drinking.
However, most people with some of the risk factors have never developed hypertension
Some researchers suggested that the rise of obesity associated with the promotion of a high-fat diet over the past decades may be the major influence on the onset of high blood pressure.

Dr. Wilde DW, the lead scientist said, “Dietary fat contributes to the elevation of blood pressure and increases the risk of stroke and coronary artery disease”.

And, “an elevation of plasma FAs may contribute to the development of hypertension via a process involving the elevation of Ca(2+) current density and alteration of channel kinetics in the vascular smooth muscle membrane”.

The onion is a plant in the genus Allium, belongings to the family Alliaceae, a close relation of garlic. It is often called the “king of vegetables” because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world’s cultures. 
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.

On finding a potent ingredient for the prevention of hypertension, researchers evaluated the effect of aqueous extract of garlic, white onion, and purple onion on subjects with blood pressure.

Elevated levels of an angiotensin-converting enzyme associated with the high blood pressure were inhibited by the aqueous extract of garlic, purple onion, and white onion in a concentration-dependent manner (0-4 mg/ml).

Additional differentiation also suggested that purple onion (IC50 = 0.59 mg/ml) had higher inhibitory effect on angiotensin-converting enzyme comapred to those of white onion (IC50 = 0.66 mg/ml) and purple onion (IC50 = 0.96 mg/ml).

Furthermore, all aqueous extracts showed a significant activity to scavenge 2,2- diphenyl-1-picrylhydrazyl (DPPH*) free radical and reduce Fe3+ to Fe2+ in a dose-dependent manner.
Based on the findings, researchers concluded, “a possible mechanism by which garlic, white onion, and purple onion exert… antihypertensive properties could be through the inhibitory effect on ACE,.. coupled with their ability to prevent lipid peroxidation in the pancreas and heart, which justify their strong antioxidant properties”.

Taken altogether, onion used alone or combined with garlic may be considered a remedy for the prevention and treatment of hypertension, pending to the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it’s news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada – Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

(1) Inhibitory Effect of Garlic, Purple Onion, and White Onion on Key Enzymes Linked with Type 2 Diabetes and Hypertension by Oboh G1, Ademiluyi AO1, Agunloye OM1, Ademosun AO1, Ogunsakin BG. (PubMed)
(2) High-fat diet elevates blood pressure and cerebrovascular muscle Ca(2+) current by Wilde DW1, Massey KD, Walker GK, Vollmer A, Grekin RJ. (PubMed)